The Detroit Lions received a major injury blow on Thanksgiving, as star wide receiver Amon-Ra St. Brown left Thursday’s game against the Green Bay Packers with an ankle injury.
The two-time All-Pro limped off the field with trainers midway through the first quarter and was immediately ruled questionable to return (now ruled out), casting uncertainty over an already injury-depleted Detroit offense.
Status alert: Amon-Ra St. Brown (ankle) won't return Thursday.
— Underdog NFL (@UnderdogNFL) November 27, 2025
Injury Occurred During Run-Blocking Sequence
The injury happened on a first-and-10 run by Jahmyr Gibbs, when St. Brown was rolled up on from behind while engaged as a blocker. After staying down for several moments, he walked to the locker room under his own power, but with a noticeable limp.
Amon Ra St Brown done before I’ve even eaten Thanksgiving dinner. My fantasy game over. Dinner ruined.
— Richard “BJ” Hardin (@RichHardin23) November 27, 2025
Before exiting, the Lions had just 10 total yards of offense and were 0-for-2 on third down, struggling to find rhythm without their top playmaker.
Lions Already Shorthanded
Detroit entered the matchup missing multiple key offensive starters, including tight end Sam LaPorta (IR, back), wideout Kalif Raymond (ankle), left guard Christian Mahogany (leg), and center Graham Glasgow (knee).
St. Brown, who has 75 catches for 884 yards and nine touchdowns this season, is the most irreplaceable piece in the passing game, making this injury especially concerning.
Amon-Ra St Brown R ankle injury video
— Jimmy Liao MD | Detroit Lions Morning Rounds (@JimmyLiaoMD) November 27, 2025
-Rolled up on which usually causes hi ankle but in this case is rolled up on inside causing inversion and more likely lo ankle sprain which is good news.
-Has a decent chance of returning assuming XR neg. pic.twitter.com/Tz3M5Z40vc
In his absence, Jameson Williams, Tom Kennedy, and rookies Isaac TeSlaa and Dominic Lovett are seeing increased roles.
Photo Credit: Junfu Han / USA TODAY NETWORK via Imagn Images
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